투석기의 종류는 무엇입니까?
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2021-12-01
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LEPU
투석기는 투석막 및 신장을 대체하기 위한 지지 구조로 구성된다. 투석막은 투석기에서 혈액을 분리하는 투석기의 주요 부분입니다. 투석 중, 혈액 및 투석액은 막의 양쪽에서 반대 방향으로 흐르고, 물과 용질은 반투과성 막을 통해 교환된다. 투석기의 성능은 투석 치료의 효과를 결정하고 혈액 투석 프로그램의 개발에 중요한 참조 요소입니다.
The characteristics of the 지혈 투석기 are composed of two parts: design characteristics and working characteristics. Design features include the configuration of the 투석기, the pre-charge of the blood chamber and the dialysate chamber, the type of membrane, and the biocompatibility. Working characteristics include the transfer rate of different solutes and water. There are several classification methods for 투석기s.
Ⅰ. 투석기의 구성에 따른 분류
Dialyzers are divided into tube type, flat type, and hollow fiber type. At present, the commonly used 투석기s are hollow fiber type, and the flat-type and tube-type 투석기s used in the early days have been basically eliminated.
The 중공 섬유 투석기 is composed of 8000-12000 hollow fibers, the fiber inner diameter is 200-300um, and the wall thickness is 2-30um. The hollow fibers are bundled into bundles and placed in the formed 투석기 casing, and the casing and the dialyzing membrane are sealed with polyurethane. The blood flows through the hollow fibers, and the dialysate flows in the opposite direction outside the fibers.
Ⅱ. 투석기의 막 재료에 따른 분류
멤브레인 재료에 따라 투석기는 4 가지 범주로 나눌 수 있습니다.
1. Regenerated cellulose membrane 투석기, including copper imitation membrane and copper ammonia membrane 투석기. There are free hydroxyl groups on the surface of cellulose, which can react with blood components and has poor biocompatibility. After the Cupra treatment, the fiber surface is smoother and the biocompatibility is improved.
2. Acetate cellulose membrane 투석기. The cellulose is acetylated before the film is formed, which improves the biocompatibility and performance of the film.
3. Replace the fiber membrane 투석기. Blood imitation membrane is an alternative copper imitation membrane because its surface-free hydroxyl groups are covered by tertiary ammonia compounds, which have good biocompatibility.
4. Synthetic fiber membrane 투석기. Materials for this 투석기 include polyacrylonitrile, polymethylmethacrylate, polysulfone, polycarbonate, polyethylene, and polyamide. They have a higher transport coefficient and ultrafiltration coefficient, better biocompatibility, but a higher price.
III. 투석기의 초여과 계수에 따른 분류
According to the ultrafiltration coefficient, there are two different 투석기 유형:
1. Low ultrafiltration coefficient 투석기. Ultrafiltration coefficient <15ml/(mmHg.h㎡), including copper imitation membrane, cuprammonium membrane, blood imitation membrane, and cellulose acetate membrane.
2. High-throughput and high-efficiency 투석기. Ultrafiltration coefficient> 15 ml/(mmHg.h㎡), has a very high removal rate for medium molecular weight substances and can remove large molecular weight β2-microglobulin and other macromolecular substances. Typical high-efficiency 지혈 투석기s include polysulfone membrane series, PAN membrane, PMMA membrane, and cellulose acetate membrane 투석기.
다음 제품에 관심이있을 수도 있습니다.
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